Facts on Neglected diseases
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Kala azar: Unaffordable drug
Access to liposomal amphotericin B, a critical drug against kala azar in South Asia, is very limited due to its high price, with treatment costing around US $200 on average per patient.Last updated 22 September 2011
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Kala azar is more difficult to treat in East Africa
Currently available medicines and rapid diagnostic tests for kala azar have shown much less efficacy in East Africa than in the Indian subcontinent.Last updated 22 September 2011
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Kala azar and HIV
People living with HIV are much more susceptible to develop kala azar, and once infected, kala azar accelerates AIDS.Last updated 22 September 2011
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Kala azar: 50,000 deaths every year
Kala azar is estimated to affect 500,000 people and to be responsible for 50,000 deaths annually, with 90% of the burden in Bangladesh, India, Nepal, Ethiopia, Sudan, South Sudan and Brazil.Last updated 22 September 2011
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Sleeping sickness: Current diagnostics are not adapted
Before NECT, a combination therapy for sleeping sickness, was developed in 2009 by DNDi and partners, therapies against late stage sleeping sickness were either very cumbersome or highly toxic.Last updated 22 September 2011
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Sleeping sickness: A fatal disease
If untreated, sleeping sickness is 100% fatal and death follows only after prolonged agony brought on by neurological disorders.Last updated 22 September 2011
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Sleeping sickness is driven by conflicts
Many people who contract sleeping sickness are located in conflict-afflicted areas with poor access to primary healthcare.Last updated 22 September 2011
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Chagas: Seeking drug suppliers desperately
As there is currently a high risk that the supply of benznidazole, the first-line medicine against Chagas disease, be interrupted, MSF had to postpone treatment for more than 150 patients in Paraguay.Last updated 22 September 2011
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Chagas: No simple test
There is no simple test that can detect Chagas disease in patients. Further, no test exists that can confirm a cure after treatment.Last updated 22 September 2011
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Chagas: 10 million people affected
Around 10 million people are infected by the parasite t. cruzi and up to one-third of them, if left untreated, will reach the late stage of Chagas disease which is accompanied by heart complications.Last updated 22 September 2011
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