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In medical journals/research articles
Earlier this year a series of advertisements appeared in London's Westminster tube stations asking viewers to consider a seemingly simple question, ‘what does it take to make one medicine?’ But as it turns out, this question is not so simple to answer. In this commentary we highlight some key considerations and questions on what it takes to make one medicine, and what it could take to develop medicines that meet people's health needs and are accessible and affordable for all who need them. Link through to Journal: Clinical Microbiology and Infection: Research & development in the dark
Last updated 16 August 2016
Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis
Link through to Journal: Centers for Disease Control and Prevention: Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis
Link through to Journal: Lancet Global Health: Disparity in market prices for hepatitis C virus direct-acting drugs
Last updated 18 November 2015
New developments in the treatment of drug-resistant tuberculosis: clinical utility of bedaquiline and delamanid
Abstract Link through to Journal: New developments in the treatment of drug-resistant tuberculosis: clinical utility of bedaquiline and delamanid
Last updated 4 November 2015
Introduction Of the 24 neglected tropical diseases (NTDs) and conditions listed by WHO, snakebite is among the top killers . Tens of thousands die each year as a result of snakebite envenoming, with close to 50,000 deaths in India alone  and up to 32,000 in sub-Saharan Africa . Yet there are few sources of effective, safe and affordable antivenoms. The regions that bear the highest snakebite burden are especially underserved .Link through to Journal: Antivenoms for snakebite envenoming: what is in the research pipeline?
Last updated 10 September 2015
Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries: A Systematic Review.
INTRODUCTION:Link through to Journal: Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries: A Systematic Review.
Last updated 2 September 2015
SummaryLink through to Journal: A Global Biomedical R&D Fund and Mechanism for Innovations of Public Health Importance
Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.
Last updated 2 December 2014
Dried blood spot in the genotyping, quantification and storage of HCV RNA: a systematic literature review
SUMMARY. The entry of new all-oral direct acting antiviral therapy for hepatitis C provides an opportunity to scale up HCV care in low- and middle-income countries. In HIV, use of dried blood spots (DBS) has facilitated the diagnosis and management of HIV in resource-poor settings. DBS may be used in a similar way to facilitate diagnosis and management of HCV. Link through to Journal: Journal of Viral Hepatitis
Objectives Further scale-up of antiretroviral therapy (ART) to those in need while supporting the growing patient cohort on ART requires continuous adaptation of healthcare delivery models. We describe several approaches to manage stable patients on ART developed by Médecins Sans Frontières together with Ministries of Health in four countries in sub-Saharan Africa. MethodsLink through to Journal: Community-supported models of care for people on HIV treatment in sub-Saharan Africa
Last updated 19 June 2014