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Research article

84 results found

Yeshiwas Tesema MSF’s community and health education supervisor speaks about the risks of snakebites to migrant workers in Abdurafi town.

Research article |

21 December 2022

Toxicon: X: Snakebite envenoming at MSF: A decade of clinical challenges and antivenom access issues

MSF authors describe medical activities for people for snakebite, including the importance of offering antivenom free of charge, though costly for MSF.

Tags Tropical & neglected diseases snakebite

Research article |

29 August 2022

Clinical Infectious Diseases: Access to medicines for treating people with cryptococcal meningitis

MSF, Unitaid and WHO authors discuss the need to improve access to liposomal amphotericin B (L-AmB) for the treatment of HIV-associated cryptococcal meningitis.

Tags HIV/AIDS cryptococcal meningitis liposomal amphotericin B UNITAIDWorld Health Organization

Dr Abdu Samya Bashagha checking X-ray scan of a patient in Abu Sitta Hospital where MSF is running TB support activities

Research article |

19 April 2022

BMJ Global Health: Recently developed drugs for the treatment of drug-resistant tuberculosis: a research and development case study

MSF authors analyse R&D and regulatory approval of DR-TB drugs bedaquiline and delamanid, and impact on treatment outcomes and access.

Tags Tuberculosis drug-resistant TB bedaquilinedelamanid research and development (R&D)

Four-year-old Cheptete Lochariang’olei was bitten by a puff adder at 9 in the morning while playing outside their home in Nadome.

Research article |

26 October 2021

Toxicon: X: Access to antivenoms in the developing world: A multidisciplinary analysis

MSF and co-authors identify solutions for access challenges to safe, effective, quality-assured antivenom products for treating snakebite envenoming.

Tags Tropical & neglected diseases snakebite World Health Organization

A nurse analyses a blood sample to perform a coagulation test following a snake bite at the Paoua hospital in northwestern Central African Republic, supported by MSF.

Research article |

25 October 2021

BMJ Global Health: Snakebites and COVID-19: two crises, one R&D opportunity

MSF, DNDi and Wellcome Trust authors identify key lessons from COVID-19 that could help accelerate snakebite antivenom products in the R&D pipeline

Tags Tropical & neglected diseases snakebite research and development (R&D)

Laboratory assistant Iuliia Karbivska is scanning an Xpert MTB/Rif cartridge for use in the GeneXpert machine provided by MSF for the laboratory of the Zhytomyr Regional TB Dispensary.

Research article |

31 August 2021

PLOS ONE: Public investments in the development of GeneXpert molecular diagnostic technology

The public investments in R&D of Cepheid’s GeneXpert diagnostic test system stands in stark contrast to its lack of affordable global access

Tags Tuberculosis GeneXpert Cepheid Time for $5

Research article |

16 August 2016

Research & development in the dark: what does it take to make one medicine? And what could it take?

Tags Intellectual property and trade access to medicinesresearch and development (R&D)

Research article |

07 April 2016

Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis

Authors: Jennifer Furin, Grania Brigden, Erica Lessem, Michael Rich, Laura Vaughan, and Sharonann Lynch Two new drugs—bedaquiline and delamanid�

Tags Tuberculosis drug-resistant TB bedaquilinedelamanid

Research article |

18 November 2015

Disparity in market prices for hepatitis C virus direct-acting drugs

Tags Hepatitis C hepatitis C daclatasvirdirect-acting antiviralssofosbuvir generic medicines

Research article |

04 November 2015

New developments in the treatment of drug-resistant tuberculosis: clinical utility of bedaquiline and delamanid

Tags Tuberculosis drug-resistant TB bedaquilinedelamanid research and development (R&D) World Health Organization

Research article |

10 September 2015

Antivenoms for snakebite envenoming: what is in the research pipeline?

Tags Tropical & neglected diseases neglected diseases antivenom Sanofi Central African RepublicSouth Sudan

Research article |

02 September 2015

Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries

Tags Vaccines pneumococcal disease vaccines

Research article |

11 May 2015

A Global Biomedical R&D Fund and Mechanism for Innovations of Public Health Importance

Tags Research and development innovationresearch and development (R&D)

Research article |

02 December 2014

Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds

Tags HIV/AIDS HIV/AIDS diagnostic tests

Research article |

04 November 2014

Dried blood spot in the genotyping, quantification and storage of HCV RNA: a systematic literature review

Tags hepatitis C diagnostic tests

Research article |

19 June 2014

Community-supported models of care for people on HIV treatment in sub-Saharan Africa

Tags HIV/AIDS HIV/AIDS

Research article |

07 February 2014

Pathway to affordable, quality-assured sources of pegylated interferon alpha for treating hepatitis C

Tags Hepatitis C hepatitis C

Research article |

14 June 2013

Access to liposomal generic formulations: beyond AmBisome and Doxil/Caelyx

Tags Tropical & neglected diseases visceral leishmaniasis (kala azar)neglected diseases Gilead

Research article |

16 May 2013

Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis

Tags HIV/AIDS HIV/AIDS antiretroviral medicinesefavirenznevirapine

Research article |

23 February 2013

Strategies for reducing treatment default in drug-resistant tuberculosis: systematic review and meta-analysis

Tags Tuberculosis tuberculosisdrug-resistant TB

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Toxicon: X: Snakebite envenoming at MSF: A decade of clinical challenges and antivenom access issues

Clinical Infectious Diseases: Access to medicines for treating people with cryptococcal meningitis

BMJ Global Health: Recently developed drugs for the treatment of drug-resistant tuberculosis: a research and development case study

Toxicon: X: Access to antivenoms in the developing world: A multidisciplinary analysis

BMJ Global Health: Snakebites and COVID-19: two crises, one R&D opportunity

PLOS ONE: Public investments in the development of GeneXpert molecular diagnostic technology

Research & development in the dark: what does it take to make one medicine? And what could it take?

Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis

Disparity in market prices for hepatitis C virus direct-acting drugs

New developments in the treatment of drug-resistant tuberculosis: clinical utility of bedaquiline and delamanid

Antivenoms for snakebite envenoming: what is in the research pipeline?

Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries

A Global Biomedical R&D Fund and Mechanism for Innovations of Public Health Importance

Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds

Dried blood spot in the genotyping, quantification and storage of HCV RNA: a systematic literature review

Community-supported models of care for people on HIV treatment in sub-Saharan Africa

Pathway to affordable, quality-assured sources of pegylated interferon alpha for treating hepatitis C

Access to liposomal generic formulations: beyond AmBisome and Doxil/Caelyx

Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis

Strategies for reducing treatment default in drug-resistant tuberculosis: systematic review and meta-analysis